{ "_id": "6a1f21c0b401979e73420713", "Package": "BIGL", "Type": "Package", "Title": "Biochemically Intuitive Generalized Loewe Model", "Version": "1.8.0", "Date": "2023-06-13", "Author": "Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov,\nRytis Bagdziunas, Stijn Hawinkel, Javier Franco Pérez", "Maintainer": "Maxim Nazarov ", "Description": "Response surface methods for drug synergy analysis.\nAvailable methods include generalized and classical Loewe\nformulations as well as Highest Single Agent methodology.\nResponse surfaces can be plotted in an interactive 3-D plot and\nformal statistical tests for presence of synergistic effects\nare available. Implemented methods and tests are described in\nthe article \"BIGL: Biochemically Intuitive Generalized Loewe\nnull model for prediction of the expected combined effect\ncompatible with partial agonism and antagonism\" by Koen Van der\nBorght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas, Maxim\nNazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017)\n.", "License": "GPL-3", "VignetteBuilder": "knitr, rmarkdown", "LazyData": "true", "URL": "https://github.com/openanalytics/BIGL", "BugReports": "https://github.com/openanalytics/BIGL/issues", "Encoding": "UTF-8", "RoxygenNote": "7.2.3", "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev", "Repository": "https://openanalytics.r-universe.dev", "Date/Publication": "2023-06-13 13:52:34 UTC", "RemoteUrl": "https://github.com/openanalytics/bigl", "RemoteRef": "HEAD", "RemoteSha": "e6e06d93482d23548b29c35ec4bffbc926bfa1f2", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-16 07:23:28 UTC", "User": "root" }, 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